Seventeen
children ages 5 to 18 in a hospital setting participated in the research
project, each spending 33 nights using the artificial pancreas (closed-loop
infusion) and 21 nights using traditional treatment (continuous infusion).
Researchers
from Cambridge University have been developing the system for years, and they
couldn’t be happier with the results. The system proved more effective than
traditional insulin pumps at regulating glucose.
"These
devices could transform the management of type 1 diabetes, but it is likely to
be a gradual process," research leader Roman Hovorka of Cambridge said in
a telephone interview with Reuters.
Rather
than taking injections at every meal, the system checks glucose levels every 15
minutes and delivers insulin accordingly. It was especially effective in
regulating nighttime hypoglycemia, maintaining normal levels 60 percent of the
time, compared to 40 percent with the pump alone.
Nighttime
hypoglycemia occurs when blood glucose falls below normal levels. It is often
the result of changes in insulin metabolism (i.e., due to exercise), and can be
difficult to balance for people with type 1diabetes.
Hovorka
says these studies will help people maintain good control and improve quality
of life for people with type 1 diabetes by reducing the risk of hypoglycemia.
"These
results suggest that closed-loop devices may be able to significantly lower the
patient's risk of developing complications later in life by reducing or even
overcoming the burden of hypoglycemia," Hovorka said in a news release
from The Lancet.
Test
your knowledge on dining out with diabetes or read the study’s abstract in The
Lancet.
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