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August 22nd, 2010

Immunotherapy Pills, Drops On the Horizon for Allergy Treatment

Recent strides in allergy treatment aim to get severe allergy sufferers up and moving with new pill and liquid (oral drop) treatments. If approved, these allergy drugs could work more effectively than and eventually replace traditional allergy shots.

Photo by: William Brawley, Flikr, Creative CommonsAllergies and hay fever can cause allergy sufferers serious discomfort. In addition to a runny nose and nasal congestion, hay fever can cause sinus pressure, itchy eyes and dark circles under the eyes called allergic shiners. Severe hay fever also can cause sleep issues and sinus infections (sinusitis), and may worsen asthma problems.

Some allergy sufferers rely on injections to address these severe symptoms, especially in the spring and fall when allergies and hay fever peak. Shots are given frequently—as often as twice weekly to twice monthly—for several years to build a tolerance to allergens. This therapy is now available orally in pill or drop form, known as sublingual immunotherapy.

Immunotherapy can cut symptoms by 20-30 percent, slightly higher than the use of nasal sprays (17 percent) and daily antihistamines (12-15 percent). Although immunotherapy drops and tablets have not yet made their way to the United States, they are already being used in Europe. Researchers are still investigating the long-term effectiveness of sublingual immunotherapy. One such investigation appears in the Journal of Allergy and Clinical Immunology.

In the meantime, you can learn more about allergy shots and how to manage allergies and hay fever from the Mayo Clinic website.

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