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Heart Diseases

Heart diseases are disorders that prevent the heart from functioning normally. The most common cause of heart disease is coronary artery disease. Other causes include congenital heart disease; hypertension; heart valve and rhythm abnormalities; and infections.

November 15th, 2009

Drink Chocolate Milk or Hot Cocoa to Prevent Atherosclerosis

Like chocolate milk and hot cocoa? You could be just two glasses a day away from a healthier heart. New information indicates that drinking chocolate milk containing cocoa could help improve abnormal blood lipid and cholesterol levels, which puts people at risk for  atherosclerosis and heart disease.

Photo by: Paul David, Creative Commons, FlikrDr. Ramón Estruch of the University of Barcelona’s Department of Internal Medicine was the study’s senior author. Estruch and his team asked 42 high-risk men and women age 55 or older to take part in an experiment examining the effects of cocoa on heart disease.

“Cocoa and its derived products, such as chocolate, represent a very rich source of dietary flavonoids, which contain a higher content per serving than tea or red wine,” authors write. “The health benefits associated with cocoa consumption have been related to their capacity to improve the lipid profile and insulin sensitivity, diminish blood pressure, reduce platelet activity and function, and ameliorate endothelial dysfunction.”

Participants were given two sachets of non-fat, sugar-free Cola Cao, a popular Spanish cocoa powder mix similar to Nesquik. They were to mix 20 g (about 1 ½ Tbs.) with 250 ml (~8.5 oz) of skim milk and drink twice daily—once with breakfast, and again with dinner or an afternoon snack. All participants followed a Mediterranean-style diet, but were asked to exclude foods with cocoa, olive oil, red wine, tea, or fruits and vegetables with high polyphenol levels.

Participants did have a slight weight gain of about 1 pound. Total cholesterol and triglyceride levels were slightly (although not significantly) lower.  Cocoa did, however, show anti-inflammatory effects. These were modest compared to those of red wine, but significant nonetheless.

HDL (good cholesterol) levels were also significantly higher after drinking chocolate milk.

“Our results suggest that regular consumption of nutritional doses of cocoa may have an effect on all initial phases of the atherosclerotic process in subjects at high risk of coronary heart disease,” authors wrote. “These anti-inflammatory effects, together with other previously reported effects, including those of antioxidant, anti-platelelet, and positive vascular effects, may contribute to the overall benefits of cocoa consumption against atherosclerosis.”

The study appears in the American Journal of Clinical Nutrition.

October 19th, 2009

Safflower Oil Helps Women with Type 2 Diabetes Lose Weight, Control Blood Sugar

A certain type of unsaturated fatty acid, CLA, and safflower oil may be key ingredients in helping postmenopausal women with type 2 diabetes drop pounds and improve blood sugar, or blood glucose, levels, according to research from Ohio State University (OSU).

Photo by: PicsmaKer, Creative Commons, FlikrAfter menopause, many women experience weight gain, which increases the risk of developing metabolic conditions. For women with type 2 diabetes, weight loss and glucose management can become extremely difficult to manage. Researchers found that both CLA and safflower oil proved particularly beneficial to postmenopausal women with type 2 diabetes.

CLA, conjugated linoleic acid, is an unsaturated fatty acid found primarily in meat and dairy products of cows, goats and sheep. CLA has been known to help people wishing to build muscle, lose weight and prevent heart disease.

Safflower oil is a plant-based oil similar to sunflower oil that is used in cooking oils, salad dressings and some margarines. Safflower oil, SAF, is a colorless and flavorless source of omega-6 fatty acids, and has been known to promote healthier skin and hair, reduce cholesterol and boost the immune system.

Thirty-five women completed a 36-week study comparing the effects of CLA and safflower oil on weight and body mass. Each supplement was consumed for sixteen weeks. Participants took roughly two teaspoons of either oil daily.

CLA began to cut body fat and reduce BMI after just eight weeks. “This magnitude of reduction has not been reported in an intervention that used a linoleic acid-rich oil,” wrote lead authors Martha Belury and Leigh Norris, both from the Department of Human Nutrition at OSU.

Safflower oil, originally meant for baseline comparison, yielded exciting changes of its own. Safflower oil reduced trunk mass and increased lean muscle mass, resulting in an average loss of 6.3 percent of body fat. It also reduced insulin resistance and fasting blood glucose levels.

“I never would have imagined such a finding,” Belury says. “This study is the first to show that such a modest amount of linoleic acid-rich oil may have a profound effect on body composition in women."

Belury and associates are pleased with the results of their study, and hope to explore the effects further. They believe that CLA and safflower oil show great promise in weight and glucose management for women with type 2 diabetes.

“It is possible that further reductions in BMI are achievable with a longer length of supplementation,” the authors wrote. “The use of lower doses of CLA over longer durations of intervention may prove to be an effective weight-loss aid."


The study appears online in The Journal of Clinical Nutrition.

October 16th, 2009

Recession Could Increase Life Expectancy

Current unemployment rates stand at nearly 10 percent, and the U.S. Bureau of Labor Statistics expects this number to continue to rise. While this has been the cause of serious worry among the labor force, there may also be a reason to celebrate. A poor economy appears to add years to a person’s life expectancy, according to research from the University of Michigan.

Photo by: Seattle Municipal Archives, Creative Commons, Flikr“While economic expansions bring with them increases in employment, greater optimism, and higher incomes (although not always and not for all sectors of the population), recessions are of periods of pessimism, shrinking, and social malaise,” study authors Jose A. Tapia Granados and Ana V. Diez Roux wrote. How, then, could this improve health?

Granados and Diez believe this may be due, in part, to the stress factors associated with economic boom. During times of economic prosperity, employees carry a much heavier workload. Higher occupational demands require workers to work quickly and put in more hours, which can cause greater stress and greater alcohol and tobacco consumption. There are also higher rates of cardiovascular problems during periods of expansion. There is less to do during times of economic downturn, which would eliminate many of these problems.

To examine the effects of recession on health and life expectancy, Granados and Diez reviewed mortality rates during the Great Depression. “Mortality tended to peak during years of strong economic expansion,” the authors wrote. “In contrast, the recessions of 1921, 1930-1933 and 1938 coincided with declines in mortality and gains in life expectancy.”

In 1932, at the height of the depression, nearly 23 percent of the U.S. population was unemployed. Life expectancy at this time was 63.3 years, up over six years from 57.7 in 1929. Not only did the weak economy seem to prolong life, but there was also a decline in tuberculosis cases, traffic accidents and pollution.

Overall statistics were consistent across age groups, gender, and whites and nonwhites, but the latter group saw the most benefit. “Nonwhite males lost 8.1 years of life expectancy between 1921 and 1926, and females lost 7.4 years (a brief period of expansion),” authors wrote. “In contrast, during the Great Depression nonwhites gained 8 years of longevity.”

Suicide rates rose during the Great Depression, accounting for less than two percent of all deaths. The economic crisis of the 1920s and 30s also saw higher rates of infant mortality and malnutrition in areas with extremely high unemployment rates, but people generally lived longer, healthier lives.

If this pattern holds true today, they say it’s possible current economic conditions could give Americans up to two additional years of life: “Although social science is not physics, regularities in the past allow us at least some confidence in forecasting the future.” They also stress that although this information is promising, the negative effects of anxiety and hopelessness can still take a toll on a person’s health and well-being.

Granados and Diaz plan to continue their research. They explain, “A better understanding of the beneficial effects of recessions on health may perhaps contribute to the development of economic policies that enhance health and minimize or buffer adverse impacts of economic expansions.”

September 29th, 2009

Smoking Bans Prove Beneficial to Heart Health

Communities are finally starting to see payoff from bans on public smoking. The bans, which prohibit smoking in restaurants, health facilities, and businesses, correspond with a decline in the rate of heart attacks.

Photo by: insomnia, Creative Commons, FlikrInformation comes from a recent study published in Circulation, a journal of the American Heart Association. The study is a compilation of nine previously published research articles on the topic. The study notes a decrease in the risk of AMI (acute myocardial infarction), another name for a heart attack.

“The risk of AMI falls rapidly after smoking cessation,” wrote study authors James M. Lightwood, Ph. D, and Stanton A. Glantz, Ph.D. And even those who never light up themselves benefit. “The effects of secondhand smoke (SHS) on many biological mediators that lead to heart disease occur rapidly and are nearly as large as those of smoking.”

Research showed an estimated 15 percent decline in the incidence of heart attacks in the first year of smoking bans alone. Three years following enforcement of the laws saw an even greater decline, roughly 36 percent, with a 40 percent drop in Montana.

Research from five European countries that have adopted similar policies was also examined in this study. Heart attack rates fell a full 11 percent in just two months following a ban on smoking in Italy. Similar statistics were found in Ireland.    

“Secondhand smoke (SHS) increases the risk of acute myocardial infarction (AMI) by 25% to 31% (1–5),” researchers* from the Kansas University School of Medicine’s Division of Cardiovascular Diseases write. “In countries where smoking prevalence is high, for example, Britain 50%, Europe 62%, and Greece 156%, versus 22% in the U.S., AMI in nonsmokers is particularly increased.”

Individuals who ceased smoking after the laws went into effect were not accounted for, and most of the statistics come from restaurant workers. Although this somewhat limits the data, researchers believe rates are underestimated and expect this trend to continue exponentially as more legislation goes into effect.

Authors of the study write, “Passage of strong smoke-free legislation produces rapid and substantial benefits in terms of reduced AMIs and that these benefits grow with time.”



*David G. Meyers, M.D, M.Ph.; John S. Neuberger, DRPH, M.Ph.; M.B.A., and Jianghua He, Ph.D

September 28th, 2009

Will Soda Pop Tax Prevent Obesity?

Legislators are considering the option of food taxes on sweetened beverages, including soda pop, and snack foods in an effort to battle obesity. Forty states are in support of a small tax on soda, while New York and Maine believe a higher tax may be necessary.

Photo by: Alan.Stoddard, Creative Commons, Flikr 
According to a report in The New England Journal of Medicine
, sugar consumption has risen 30 percent over the last decade. For teens and children, soda accounts for 10-15 percent of total calories consumed. By removing just ¼ of the sugar in sweetened beverages, consumers can reduce annual caloric intake by 8,000 calories. This figure equates to roughly two pounds of weight in a year.

“Americans consume about 250 to 300 more calories daily today than they did several decades ago,” according to authors Kelly D. Brownell, Ph.D., and Thomas R. Frieden, M.D., M.P.H. “Though no single intervention will solve the obesity problem, that is hardly a reason to take no action.”

Such a high rate of sugar intake can do more than expand the waistline. It can also increase the risk of type 2 diabetes, heart disease, and other problems as a result of poor nutrition and weight gain. The objectives of those in support of a tax are twofold—to lower consumption, and to encourage soft drink producers to decrease the amount of caloric sweeteners in their products.

There are strong arguments on both sides. People arguing against the tax point out that food is necessary to survive. They believe raising prices will make it more difficult for low-income families to eat. Others argue that the poor would benefit the most. As the price of fresh produce and other healthier options goes up, soda and junk food prices are going down. People with tighter budgets consume more of the cheap but less nutritious foods and beverages.

“As Coca-Cola prices increased by 12 percent, sales dropped by 14.6 percent,” Frieden and Brownell wrote. Analysts believe that a 1 cent-per-ounce price increase could reduce consumption by as much as 10 percent. Justin Wilson, senior research analyst for the Center for Consumer Freedom, argues that such a tax is manipulation against the consumer. “The tax code should not be used as a method for social engineering, and that’s what this is,” he said.  Legislators see the issue a little differently.

Higher prices have been used effectively in the past to reduce tobacco sales, and any revenue from a tax on soda could raise up to $14.9 billion per year. This money could be used to support health reforms or other programs. New Yorkers’ support rose by 20 percent when lawmakers suggested using these funds for obesity prevention programs.
September 5th, 2009

Feeling Hopeless Could Put You at Greater Risk for Stroke

Hopelessness may increase your risk of stroke, according to new information from the University of Minnesota. Researchers found that higher levels of hopelessness are linked with accelerated development of early atherosclerosis in middle-aged women.

Photo by: D. Sharon Pruitt, Pink Sherbet Photography, Flickr, Creative CommonsAtherosclerosis causes plaque to build up on the insides of arteries, reducing the flow of oxygen-rich blood to organs and other parts of the body. Arteries in the neck can thicken, a condition called carotid artery intimal-medial thickening (IMT). Atherosclerosis increases risk of heart attack and can block blood flow to the brain and lead to stroke.

Science has explored the connection between hopelessness and IMT in men and women with cardiovascular disease, but little was known about the link in healthy women. “This is the first study to suggest that hopelessness may be related to subclinical cardiovascular disease in women without clinical symptoms of heart disease,” said Susan A. Everson-Rose, Ph.D., M.P.H., associate professor of medicine at the University of Minnesota and co-author of the study.

Data for the study was collected from two sites in Chicago and Pittsburgh, using the Study of Women’s Health Across the Nation (SWAN). Five hundred and fifty-nine women (average age 50) living in the city participated in the study. Participants appeared to be in good health, showing no signs of cardiovascular disease.

SWAN used questionnaires to measure the association between IMT and hopelessness frequency using an eight-point scale, asking participants about personal goals and future life expectations. Scores of five and above were considered “high.” Ultrasounds were then used to measure the thickness of arteries in the neck.

Participants with the highest hopelessness scores showed an average of .06 mm greater thickening than their hopeful counterparts (.02 mm is equal to roughly one year’s thickening). Researchers discovered that hopelessness triggered a hormonal release in response to mood change that can amplify the effects of atherosclerosis and the thickening of neck arteries.

Researchers plan to continue exploring the unique relationship between hopelessness and cardiovascular disease in future studies. “These findings suggest that women who experience feelings of hopelessness may have greater risk for future heart disease and stroke,” Everson-Rose said. "We look forward to examining the longitudinal relations between hopelessness and heart disease risk in women."

August 26th, 2009

Glucose Intolerance During Pregnancy May Boost Risk of Heart Disease

Glucose intolerance during pregnancy may put women at greater risk for heart disease. According to Baiju Shah, MD, PhD, FRCP, of the Institute for Clinical and Evaluative Sciences in Toronto, co-author of a recent study on women with gestational diabetes, even mild glucose intolerance—below the threshold for gestational diabetes—increases the chances of later cardiovascular disease. 
Photo by: atomicpuppy68, Flickr, Creative CommonsGestational diabetes had been connected to cardiovascular disease prior to this study, but little was known of the links between minor glucose intolerance and heart disease. Type 2 diabetes and cardiovascular disease share several characteristics including obesity, insulin resistance and cholesterol problems. Oftentimes, individuals with one condition will develop the other. Women with gestational diabetes may experience similar metabolic complications as soon as 3 months after giving birth.

Researchers analyzed the medical records of all Ontario women between the ages of 20 and 49 who had given birth between April 1994 and March 1998.  Participants were divided into three groups: those who were diagnosed with gestational diabetes, those who received an oral glucose tolerance test, and those who were not screened using oral glucose testing. One birth was selected at random for women with multiple deliveries; the median ages were between 29.2 and 31.1.

Women are tested for gestational diabetes (a type of diabetes that develops when women experience unusually high glucose levels during pregnancy) during the second trimester of pregnancy (13-27 weeks). The first step is a glucose challenge test, taken by measuring glucose levels one hour after ingesting a sugary substance such as glucola. If results are abnormal (≥7.8 mmol/L), a second oral glucose tolerance test (OGGT) is taken.

Participants in the study were followed up until March 31, 2008, providing information reflecting cardiovascular disease development for a median of 12.3 years after childbirth. “If you followed 10,000 people for one year, 4.2 of them would have an event,” Dr. Shah explains. “If you followed those 10,000 people for 10 years, 42 of them would have an event…In other words, these are extremely rare events.”

Although the differences were minor—absolute risk was 0.16% and 0.05% for women with gestational diabetes and women who received an OGGT, respectively—the results indicate a need for further research. "We shouldn't be ignoring these mild abnormalities during pregnancy,” Dr. Shah says. “(They) may benefit from extra surveillance and/or cardiovascular disease screening.”

More information is needed to establish the exact relationship between glucose intolerance and cardiovascular disease. In the meantime, proper nutrition and exercise may reduce your risk for both gestational diabetes and cardiovascular disease.


Read more about gestational diabetes and cardiovascular disease.

August 6th, 2009

U.S. Children Not Getting Enough Vitamin D

Seven in ten children in the United States are not getting enough vitamin D, according to the National Health and Nutrition Examination Survey (NHANES, 2001-2004).
Photo by: Tsuacctnt, Flickr, Creative Commons
Vitamin D, 25-Hydroxyvitamin D, is a fat-soluble vitamin that promotes calcium absorption, fortifying bones and teeth, and maintaining the level of calcium and phosphorus in the blood.

Vitamin D deficiency can result in conditions such as rickets in children (usually <11 ng/mL), and osteomalacia and osteoporosis in adults (typically levels <25 ng/mL). Low levels of vitamin D also increase the risk of bone and heart disease, and are also associated with higher blood pressure and lower calcium and HDL cholesterol levels in later life.

Based on the information obtained from the survey, researchers found that, of more than 6,000 of children followed, nine percent (equal about 7.6 million) were vitamin D deficient, and a greater number were found to be getting an insufficient amount—61%, representing 50.8 million U.S. children. Only 4% received the recommended daily amount of vitamin D.

Children classified as “insufficient” had 15-29 ng/mL, while those who were classified as “deficient” had levels of 15 ng/mLor less. Normal range, according to the National Institute of Health, is 30-74 ng/mL.

The study is the largest of its kind to date, gaining nationwide rather than just regional data. "We expected the prevalence of vitamin D deficiency would be high,” says lead author Juhi Kumar, M.D., M.P.H., of the Children's Hospital at Montefiore Medical Center, “but the magnitude of the problem nationwide was shocking."

Vitamin D deficiency is more common for female children, those that are older, obese, drink less than one glass of milk week, and those who spend four hours or greater on the computer or watching television per day. African-American and Mexican-American children also had a greater risk.“It’s very hard to get enough vitamin D from dietary sources alone,” says Dr. Michal Melamed of the Albert Einstein College of Medicine in Bronx, New York.

Melamed, co-leader of the study, attributes part of this problem to lifestyle, recommending parents send their children outdoors. One source of vitamin D is UV-B sunlight, which converts cholesterol in the skin into vitamin D. She also recommends ditching the sunscreen for a while: “Just 15 to 20 minutes a day should be enough…don't put sunscreen on them until they've been out in the sun for 10 minutes, so they get the good stuff but not sun damage.” Individuals with darker skin and those who live in northern regions with less sun exposure should spend more time outdoors.

The American Academy of Pediatrics recommends that children and teens get at least 400 IU per day, double the previous recommendation of 200IU per day. Good sources of vitamin D include fish, milk, eggs, cod liver oil, and fortified foods. Vitamin D levels can also be increased with the use of supplements.

The study's abstract is available online, and will be published in September's issue of Pediatrics.

May 11th, 2009

Heartburn Medications Increase Likelihood of Heart Attack in Patients Taking Anticlotting Drugs

A recent study conducted by the Indiana University School of Medicine and Medco Health Solutions Inc. suggests that taking heartburn medications while using anticlotting drugs called clopidogrel can increase patients’ likelihood of heart attack by 50 percent. The Society for Cardiovascular Angiography and Intervention recommends patients taking anticlotting drugs discontinue the use of heartburn medications called proton-pump inhibitors.

Patients who have experienced a heart attack or stroke, or who have a heart stent to treat blocked arteries often take anticlotting drugs. Doctors commonly prescribe the proton-pump inhibitors when patients experience side effects like acid reflux and stomach bleeding while taking clopidogrel. No risk has been identified in taking heartburn medications alone.

The society suggests patients use alternative treatments for bothersome gastro-intestinal side effects. Effective medications include over-the-counter antacids and prescription heartburn medications.

Challenge your heart disease knowledge using the Healia Heart Diseases Quiz. If you need more information on heart diseases and treatments, check out the Healia Heart Disease Health Guide. Share your personal experiences with heart disease medications at the Healia Heart Diseases Online Health Community and Support Group.


Photo: Publik15, Flickr, Creative Commons
April 20th, 2009

Can Blueberries Help Reduce Belly Fat and Lower Heart Disease and Diabetes Risk?

woman holding blueberriesA new animal study suggests that eating blueberries may help reduce belly fat and lower the risk for heart disease and diabetes. Researchers the University of Michigan Cardiovascular Center compared the effects of adding powered freeze dried blueberries in low- or high-fat diets fed to lab rats. After 3 months, the rats that ate the diets with blueberry powder had less belly fat, lower triglycerides and cholesterol levels, and improved fasting glucose and insulin sensitivity, compared to the rats that did not eat blueberry powder. The study results were presented yesterday at the Experimental Biology meeting in New Orleans.

The study investigators rats believe that their rat model is similar to people who are obese and have multiple risk factors for heart disease and diabetes such as increased belly fat, high blood pressure, and high blood sugar and triglyceride levels.

The study was funded by the U.S. Highbush Blueberry Council, but they apparently were not involved in the conduct or interpretation of the study results.

One of the researchers, Dr. Steven Bolling, was quoted in a press release: “The benefits of eating fruits and vegetables has been well-researched, but our findings in regard to blueberries shows the naturally occurring chemicals they contain, such as anthocyanins, show promise in mitigating these health conditions.”

Anthocyanins, a type of phytochemical, are natural pigments that are responsible for the color of red and purple fruits and vegetables, including blueberries, cherries, raspberries, beets, and purple grapes. Anthocyanins have received recent attention for their possible health effects because they are strong antioxidants.

Although previous animal studies have documented some health benefits of blueberries against cancer and the effects of aging, more research is needed to confirm their possible benefits in people. Find out more about healthy eating in our diet and nutrition guide or get valuable tips from the Healia diet and nutrition community.  
 

Photo: D. Sharon Pruitt, Flickr, Creative Commons

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