Shannon
suffers from a rare type of leukemia known as acute myelogenous leukemia (AML).
Early symptoms of the disease—fever, fatigue, paleness, bone and joint pain,
and infections—are easy to confuse with more run-of-the-mill illnesses like a
cold or the flu. That’s what Shannon’s mother thought.
“I
started noticing she was very tired and fatigued, and it wasn’t normal,”
Shannon’s mother, Odiney Brown, told ABC News. “The day we found out, we
immediately admitted our lives had just changed completely.”
AML can
quickly go from bad to worse. In order to recover, Shannon will need a bone
marrow transplant, and like so many others with the condition, she now
struggles to find a donor. Finding an exact match won’t be easy, either,
because Shannon is African American and Hispanic—two highly underrepresented
donor groups.
Even in
the event that a donor is found, it is likely that Shannon will need additional
treatment. “It is generally an aggressive disease that requires chemotherapy,”
Shannon’s doctor, Dr. Barbara Asselin of Golisano Children’s Hospital at the
University of Rochester Medical Center, told ABC News. “The first hurdle is to
see if we can achieve a remission in the bone marrow and don’t see any more
leukemia cells.”
Asselin
says the chances of recovery are less than other forms of childhood leukemia,
but that she remains optimistic about a cure. For now, Shannon is trying to
enjoy life as a normal 11-year-old girl, watching movies at home and chatting
online with friends between treatments.
Read more
from ABC, or find out how to become a donor through the National Marrow Donor
Program.
Breast
cancer forms in the mammary glands and/or ducts. Tissues in these areas grow
and multiply at unregulated rates, forming tumors. The body recognizes these
tumors as healthy tissues and will not destroy them as it would a virus.
According to the Susan G. Komen Foundation, it could take as long as 10 years
before a tumor is large enough to detect.
Most
current efforts to treat breast cancer focus on how to destroy or stop the
growth of already-present cancer cells using tumor antigens. The problem is
that these methods essentially kill the tissues. It can also compromise the
autoimmune systems of already vulnerable cancer patients. The Cleveland Clinic's
vaccine takes a new approach: It’s designed to stop tumors before they’ve had a
chance to develop.
Lead
researcher Dr. Vincent Tuohy observed mice predisposed to breast cancer for 10
months. The vaccine targeted alpha lactalbumin, a specific protein found in
most breast cancer cells. Half of the mice were given the vaccine, while the other
half acted as a control group. At the end of the trial, none of the vaccinated
mice had developed breast cancer. All of unvaccinated mice had.
"We
believe that this vaccine will someday be used to prevent breast cancer in
adult women in the same way that vaccines prevent polio and measles in
children," Tuohy said in a Cleveland Clinic press release. "If it
works in humans the way it works in mice, this will be monumental. We could
eliminate breast cancer."
Although
there is still much more to investigate before the vaccine is ready for human
trials, the research team hopes to be able to administer the vaccine to women older
than 40 and women at high risk in the next 10 years.
Visit the
Cleveland Clinic’s website to read the press release,
or visit Nature Medicine to read the study’s abstract.
The technique involves stimulating dormant ovarian follicles, also known as Graafian follicles. These follicles are small spherical cavities that fill with fluid to develop eggs. Once the egg is developed, the woman ovulates and prepares for fertilization.
If these
follicles are damaged, however, a woman may not produce eggs and may experience
infertility. Only a small portion of ovarian follicles are used each month, and
some remain dormant over the course of a woman’s life. Researchers hoped that
by stimulating these follicles, they could boost fertility.
Researchers first
tested the technique on mice and were successfully able to produce mature eggs
and then pups. They were also able to produce eggs in humans, but did not
investigate the technique’s effects on conception.
Experiments are
still in the early stages, but these results do provide hope for couples
struggling with fertility. Lead author of the study, postdoctoral fellow Jing
Li of Stanford University Medical School, says it will be a while before they
know whether this method will be as successful in humans as it is in mice.
“We
hope that aging women, women who have frozen ovarian tissues prior to
undergoing cancer treatments, or women with premature ovarian failure could
benefit from our research," Li told Health Day.
Read the original
article in Health Day, or visit The Proceedings of the National Academy of
Sciences to view the
study’s abstract.
If you're having trouble keeping your daughter out of the tanning bed, and talking to her about cancer isn't helping, you may consider stressing wrinkles as a consequence of too much tanning time.
To test the effectiveness of an appearance-based
intervention, Dr. June Robinson, professor of dermatology at Northwestern
University Feinberg School of Medicine, and her colleagues assembled a 25-page
book detailing the history of tanning and the effects it can have on skin and
collagen, as well as tanning alternatives. They distributed the booklets to
college-aged women (18-22) who tanned as often as four times per week.
These women said they tanned for one of two
reasons: To boost mood (symptomatic of seasonal affective disorder), or because
they detested their skin color. Six months
after reading the booklet, tanning visits among the young women fell by roughly
35 percent and some eventually gave up tanning all together. Why?
“They’re not worried about skin cancer, but they
are worried about getting wrinkled and being unattractive,” Robinson said in a
press release. “The fear of looking horrible trumped everything else.”
East Tennessee State University’s Joel Hillhouse,
Ph.D, was lead author of the report, and wrote the booklet used in the study. He
says this experiment was originally meant to serve as an appearance
intervention, which means it would have less of an effect on the group with
symptoms of seasonal affective disorder (SAD).
"We found the opposite,” he said. “The intervention worked
just as well for people with seasonal affective disorder as for people who
didn't like their skin color. That means it's a really good intervention for
everyone."
That
includes your daughter, your niece, or maybe even your sister. According to the
Skin Cancer Foundation, the number of women under age 40 diagnosed with basal
cell carcinoma has doubled in the last three decades, and the risk of melanoma
increases by 75 percent if she has used a tanning bed before age 35. Talking
about responsible tanning is important.
The
key?
"You have to balance the positive and the negative forces
that motivate someone to change," Robinson said. "First you have the
fear that they will look horrible, then you offer a positive—an alternative to
meet their needs."
Read
The Archives of Dermatology for more about the intervention study, or visit
the
Sinusitis
occurs when the sinuses become swollen or infected. According to Mayo Clinic,
sinusitis is usually the result of a cold, allergies or other nasal problems,
and can easily be treated with antibiotics, heat (to relieve sinus pressure) or
a variety of over-the counter medications.
When
the condition persists for more than eight weeks or recurs frequently, this is
known as chronic sinusitis. Secondhand smoke contains over 50 known
carcinogens; these chemicals can also cause heart problems, asthma attacks and
nasal irritation.
Researchers
from the Henry Ford Health System in Detroit, recruited 612 non-smokers
to participate in a study investigating the relationship of secondhand smoke
(SHS) and its source to chronic sinusitis. All had been exposed to SHS for five
years prior to the study, and half had been diagnosed with chronic sinusitis
(CRS).
Researchers focused on four locations where participants
were primarily exposed—home, work, public places and social functions. All
showed a marked relationship between secondhand smoke exposure and incidence of
chronic sinusitis, especially at social functions (51 percent) and in public
places (90 percent).
Although
levels of exposure were significantly lower for nonsmokers who had not been
diagnosed with chronic sinusitis, study co-author Amanda Holm, MPH, says even
modest levels of exposure carry risk.
"The
poisons found in secondhand smoke are quite an irritant to the sinus and nasal
passages and are a major contributor to the development of
rhinosinusitis," Holm said in a press release. “"Our findings
reaffirm the health hazards of secondhand smoke."
Visit
Mayo Clinic to learn more about chronic sinusitis, or learn more about Holm’s
study in The Archives of Otolaryngology.
Comparing
Apples to Oranges: UVA&UVB Rays
According
to The Skin Cancer Foundation, long-wave UVA rays make up about 95 percent of the
UV rays that hit Earth. These rays aren’t as intense, but there are 30-50 times
more of them, and they’re present year-round in all daylight conditions. UVA
rays have deeper penetration, too, and can cause wrinkles, aging, and skin
cancer.
Although
the effects of UVB rays are more superficial, they can cause serious damage to
the epidermis. These rays are responsible for skin reddening and those nasty
sunburns you get at the beach. UVB damage is more visible, and can also lead to
skin cancer.
SPF:
Get to Know Your Sunscreen
“For
sunscreen to be really effective in preventing skin cancer, it has to provide
broad-spectrum coverage,” Dr. Henry Lim, chairman of dermatology at Henry Ford
Hospital, told MSNBC. “The U.S. is the only country with no guidelines for UVA
protection, so consumers here have no way of knowing.”
One
common misconception about a sunblock’s sun protection factor (SPF) is that
the numbers—15, 30, and clear up to 100—indicate the level of protection. In
actuality, it represents the amount of time a person can be exposed before the
skin starts to redden. Dr. James Spencer, a St. Petersburg, Florida,
dermatologist explains:
“SPF
is very misleading,” he told MSNBC. “If I were a logical consumer, I would
think that SPF 30 is twice as good as SPF 15. But SPF 15 blocks 94 percent of
UVB rays. SPF 30 blocks 97 percent. Past 30, there isn’t much additional
benefit to be had.”
Where
to go from here:
The
best thing you can do for your skin is to protect against both UVA and UVB rays.
Seek shade during peek daylight hours
(10 am to 2 pm), wear clothing that will cover or protect the skin, and find a
sunscreen that has ingredients that protect against both UVA and UVB rays.
These ingredients include dioxybenzone, ecamsule, oxybenzone, titanium dioxide
and zinc oxide.
Read more about UV rays at MSNBC.com, or contact the FDA about establishing guidelines for UVA protection.
Nearly
4,900 men and women age 18 or older were randomly chosen to participate in a
University of Oslo study examining the effects of certain habits—smoking,
excessive alcohol consumption (3 or more drinks for men, and two or more for
women), getting less than 2 hours of exercise per week, and not eating well
(specifically, not enough fruits and vegetables).
The
study began in 1985, and followed participants for 20 years, checking death
certificates and doing follow-ups. Of the 314 participants who had all four
habits, almost one-third died over the duration of the study, while less than
10 percent of the 387 people who had none passed away.
Heart
disease and cancer topped the list for cause-of-death for people who had a
combination of these habits, while the health of those still living was
“equivalent to being 12 years older” than their healthier
counterparts.
Lead
researcher Elizabeth Kvaavik thinks these findings may be the extra incentive
some people need to improve their lifestyles.
"You
don't need to be extreme to be in the healthy category,” Kvaavik said in a news
piece by MSNBC. "These (healthy) behaviors add up, so together it's quite
good…It should be possible for most people to manage."
Kvaavik
and her colleagues acknowledge that changing these habits may not be easy, but
that they pay off.
“The combined effect of poor health
behaviors on mortality was substantial, indicating that modest, but
sustained, improvements to diet and lifestyle could have significant
public health benefits,” authors of the study concluded.
Visit
the Archives of Internal Medicine to read more on the study.
Ricky Durham
created the site in 2004 in honor of his brother, Keith. The site is geared to
match people with special health needs to others with similar conditions.
Whether this search is for friendship or something more is entirely up to the
user.
Ricky’s brother
Keith had Crohn’s Disease, a form of irritable bowel disorder. It could make
meeting people for the first time awkward. That’s when Ricky came up with the
idea for Prescription 4 Love.
“Deciding when to
tell someone you have a colostomy bag is incredibly difficult,” Durham
explains. “I thought if Keith had a chance to meet someone with a similar
condition, there would be no need to have to disclose anything.”
Prescription 4
Love is set up like most other online dating sites. Users can create their own
profiles, browse through the forums, and chat with each other in an open
environment without a hidden medical history. Durham’s recently added instant
messaging, blogging and virtual gifts to the mix.
Durham’s site
began with a focus on just 11 chronic illnesses, but has expanded to include
more than 30. Prescription4Love welcomes anyone from amputees to recovering
alcoholics, people with diabetes or heart disease, people who have or have had
cancer to little people. Durham has even added STDs to the list. In fact, HIV
and herpes are among his most popular groups.
“One lady in
particular called me who had cancer said that whenever she told the person she
was dating she had cancer they stopped dating her within a matter of days,” he
says. Now she can find acceptance in a community where everyone can relate in
one way or another.
As of now more
than 8,000 people have used the site, and although Keith passed away before the
site was fully developed, he is still very much the driving force behind Ricky’s
work.
“Keith is the
inspiration behind everything that I do for Prescription4Love,” he says. “I
have had phone calls and emails from different people thanking me for stating
such a web site…the response has been great.”
The purpose of the study, which appears in Neurology, was to discover whether or not cancer was linked
with Alzheimer’s and types of vascular dementia, such as Parkinson’s disease. There was
no significant relationship between Alzheimer’s and vascular dementia, but they
were able to link cancer and Alzheimer’s disease.
Researchers made adjustments for factors such as smoking, obesity, and physical activity. They also adjusted for hypertension, diabetes, and coronary heart disease. Researchers monitored 3,020 people, age 65 or older, for dementia and cancer, for roughly five and eight years respectively.
“Prevalent cancer was associated with reduced risk of any Alzheimer's disease and pure Alzheimer's disease among white subjects after adjustment for demographics,” authors wrote. “The opposite association was found among minorities, but the sample size was too small to provide stable estimates.”
White participants who’d had cancer before or at the
beginning of the study were 43 percent less likely to develop Alzheimer’s
disease. In turn, those with Alzheimer’s had a 69 percent decreased risk of
developing cancer.
Despite not finding a direct link between Alzheimer’s and
vascular dementia, the study does provide implications on its relationship to
cancer.
“Together with other work showing associations
between cancer and Parkinson disease, these findings suggest the
possibility that cancer is linked to neurodegeneration,” authors concluded.
View the study’s abstract in the online version of Neurology.
A study in the Journal of General Internal Medicine. investigates the effects
different herbal supplements on blood lead
levels. Supplements with high heavy metals levels included Ayurvedic herbs,
echinacea, ginseng, St. John’s wort, bee pollen, ginko, and nettle.
Lead exposure can result in
medical complications, including high blood pressure, kidney disease, cancer,
heart disease and peripheral artery disease. High blood lead levels also pose a
risk for women planning to become pregnant. Lead can lead to pregnancy
complications for both the mother and the developing child.
“Among
adults, the potential implications of low-level lead exposure are most relevant
to women of child-bearing age,” study authors write. “As lead is especially
harmful to developing nervous systems of fetuses and children and passes through
the placenta and breast milk.”
Researchers recruited
6,712 Unites States women in good health who were of reproductive age—20 or more
years old. Participants self-reported their vitamin regimen for 30 days, and
were divided into groups based on the type of supplements they used.
Women who took these
supplements had significantly higher lead levels than women who took other
herbal medicines. Blood lead levels of women who took Ayurvedic supplements
were 24 percent higher than non-users. St. John’s wort wasn’t far behind with
23 percent higher levels.
Greater lead levels were not
seen in individuals who used other supplements, such as garlic. Researchers
acknowledge that these supplements can have some beneficial effects on personal
health, but recommend firmer regulations.
“Our data
suggest testing guidelines for herbal supplements,” they write, “and regulations
limiting lead in supplements are needed.”
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