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Ovarian Cysts

Ovarian cysts are fluid-filled sacs located on the ovaries and in most instances do no harm and go away by themselves.

May 21st, 2010

New Follicle Stimulation Technique May Boost Fertility

Researchers from Stanford University may have discovered a way to boost fertility by stimulating dormant ovarian follicles. This could benefit women whose reproductive systems have been affected by ovarian cancer or ovarian failure.

The technique involves stimulating dormant ovarian follicles, also known as Graafian follicles. These follicles are small spherical cavities that fill with fluid to develop eggs. Once the egg is developed, the woman ovulates and prepares for fertilization.

Photo by: GabrieleRosa56, Flikr, Creative CommonsIf these follicles are damaged, however, a woman may not produce eggs and may experience infertility. Only a small portion of ovarian follicles are used each month, and some remain dormant over the course of a woman’s life. Researchers hoped that by stimulating these follicles, they could boost fertility.

Researchers first tested the technique on mice and were successfully able to produce mature eggs and then pups. They were also able to produce eggs in humans, but did not investigate the technique’s effects on conception.

Experiments are still in the early stages, but these results do provide hope for couples struggling with fertility. Lead author of the study, postdoctoral fellow Jing Li of Stanford University Medical School, says it will be a while before they know whether this method will be as successful in humans as it is in mice.

“We hope that aging women, women who have frozen ovarian tissues prior to undergoing cancer treatments, or women with premature ovarian failure could benefit from our research," Li told Health Day.

Read the original article in Health Day, or visit The Proceedings of the National Academy of Sciences to view the study’s abstract.

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